|
KMID : 1214920220280020137
|
|
Soonchunhyang Medical Science
2022 Volume.28 No. 2 p.137 ~ p.140
|
|
|
A Case of Hyperinsulinemic Hypoglycemia in Premature Infant Treated with Oral Diazoxide
|
|
Pyeon Jeong-Eun
Jeong Hwal-Rim
Koh Ji-Won
|
|
|
Abstract
|
|
|
|
Neonatal hyperinsulinism, whether permanent or transient, results in prolonged hypoglycemia, which increases the risk of hypoglycemic brain injury. Therefore, prompt diagnosis and management of hyperinsulinemic hypoglycemia is important. Drawing a “critical sample” at the time of hypoglycemia is useful for diagnosis. Genetic testing for defective insulin-regulating genes in pancreatic beta-cells might also be helpful in cases of prolonged hypoglycemia. High-calorie feeding or glucose infusion is necessary to maintain normoglycemia. Diazoxide is the treatment of choice for hyperinsulinism and should be continued until the hypoglycemia resolves. We describe a case of transient neonatal hyperinsulinemia hypoglycemia in a small-for-gestational-age preterm infant who underwent diazoxide treatment and achieved a favorable outcome.
|
|
|
KEYWORD
|
|
|
Newborn infant, Hyperinsulinism, Hypoglycemia, Diazoxide, Case report
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|